Australian - Scientist | November 26, 1948 -
Researchers have found that the brain definitely sends nerves directly to organs of the immune system and not just to the heart and the lower gut. In that way, too, the brain is influencing the body.
Elizabeth Blackburn
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In the 1970s, I did a Ph.D. with Fred Sanger in Cambridge who was in the process of inventing ways to map what's inside DNA. He later won the Nobel Prize.
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We and other groups are seeing clear statistical links between telomere shortness and risk for a variety of diseases that are becoming very common, such as cardiovascular disease, diabetes and certain cancers.
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The conservative statement is that telomere length is a biomarker, but it's probably not passive. There are some very intimate relationships between things such as molecular markers for inflammation and telomere health.
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Challenges in medicine are moving from 'Treat the symptoms after the house is on fire' to 'Can we preserve the house intact?'
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When scientists get old, they get interested in the brain, and I'm a little bit afraid I'm falling into that.
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I decided I wanted to go to Cambridge, and then I got introduced to Fred Sanger. I was very conscientious, and I asked him when I first got there if I should start reading up on things. But he said, 'No, I think you can just start these experiments,' so I plunged right in.
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At Cambridge, there was a completely unintimidating culture, and there were no class divisions among the students.
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I'm pretty good about getting some exercise every day - well, most days. The secret for me was to put the elliptical in front of the TV.
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We think there are lifestyle factors that boost telomerase naturally.
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Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person. If telomeres are up for one cell type, they're up for others overall.
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We're involved in a very large study that's federally funded and being done with Kaiser Permanente, and saliva is a very non-invasive way to get cells from the body.
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