American - Scientist | 1955 -
Sugar is the new tobacco.
Cynthia Kenyon
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We are trying to find drugs, small molecules, that people could take to make them disease-resistant, more youthful and healthy. Eventually we will find them.
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It is unlikely that changes in telomeres are influencing the lifespan of the worm. That is because telomeres only shorten when cells divide. Most of the cells of the worm stop dividing when the worm becomes an adult.
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If the aging process is controlled in a similar way in worms and humans, then we can use what we learn about worms to speed our study of higher organisms.
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If I were a worm, I would rather be the long-lived mutant than the normal worm, that's for sure.
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In principle, if you understood the mechanisms of keeping things repaired, you could keep things going indefinitely.
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The public is absolutely fascinated by aging. They don't want to get old. And you can see - read Shakespeare. Read the sonnets. They're all about aging.
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With worms you can just change genes at random and see if you can find a mutant that does what you want it to do.
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Generally, older people in their fifties, sixties, and seventies are running most countries and are CEOs of corporations. Which isn't to say there aren't entrepreneurs, but if the young were better in every respect, there'd be no reason for the old. Our life span reflects our particular life strategy.
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Age is the biggest risk factor for many diseases. You're 100 times more likely to get a tumor at age 65 than age 35. It makes a huge difference. It gives a whole new meaning to preventive medicine.
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I eat some fruit every day, but not too much and almost no processed food. I stay away from sweets, except 80 per cent chocolate.
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You could have two completely different careers if you could stay healthy to 90. How fascinating that would be.
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