American - Scientist | October 14, 1946 -
I think I've achieved some good things; doing the first genome in history - my team on that was phenomenal and all the things they pulled together; writing the first genome with a synthetic cell; my teams at the Venter Institute, Human Longevity, and before that Celera.
Craig Venter
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Our genomes are evolving and changing every single day.
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The interpretation of medicine today is 'do your clinical values fall within a normal range?' Everything in the globe right now is in the law of averages, which mean absolutely nothing to individuals.
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Genomics are about individuals. It's about what's specific to you, not your siblings, not your parents - each of us is totally unique. We will only see that uniqueness by drilling down to the genetic code.
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We can now diagnose diseases that haven't even manifested in the patient, and may not until the fifth decade of life - if at all.
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We're moving from reading the genetic code to writing it.
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Carole Lartigue led the effort to actually transplant a bacterial chromosome from one bacteria to another.
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Early on, when you're working in a new area of science, you have to think about all the pitfalls and things that could lead you to believe that you had done something when you hadn't, and, even worse, leading others to believe it.
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Mathematicians have been hiding and writing messages in the genetic code for a long time, but it's clear they were mathematicians and not biologists because, if you write long messages with the code that the mathematicians developed, it would more than likely lead to new proteins being synthesized with unknown functions.
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There are enzymes called restriction enzymes that actually digest DNA.
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We have trouble feeding, providing fresh, clean water, medicines, fuel for the six and a half billion. It's going to be a stretch to do it for nine.
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The pace of digitizing life has been increasing exponentially.
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